Kisspeptin-10

• GPR54 (KISS1R) receptor binding and signal transduction studies
• HPG axis modulation and GnRH pulse dynamics research
• LH and FSH regulation and gonadotropin feedback investigation
• Metabolic-reproductive crosstalk research (leptin, insulin, energy homeostasis)
• Neuroprotection and CNS kisspeptin signaling models
• Tumor suppression and metastatic signaling research (KISS1 metastasis suppressor)

Handle under aseptic conditions in accordance with laboratory safety protocols. Lyophilized material should be stored at -20°C protected from light and moisture. Reconstitute by injecting bacteriostatic water (BAC water) slowly along the vial wall and swirling gently — do not vortex. Once reconstituted, store at 2–8°C and use within 30 days; aliquot to avoid repeated freeze-thaw cycles. Refer to the Certificate of Analysis (CoA) for batch-specific handling recommendations. For laboratory research use only — not for human consumption, veterinary use, or food and drug applications.

• What is the intended use of this compound? For laboratory research use only. Not for human or veterinary use.
• Is a Certificate of Analysis available? Yes, each lot is supplied with a CoA documenting purity and identity confirmation by independent third-party HPLC and mass spectrometry.
• What reconstitution buffer is recommended? Bacteriostatic water (BAC water) is the most commonly referenced solvent in published kisspeptin research protocols. Sterile water or PBS may also be used depending on the assay format.
• How does Kisspeptin-10 differ from Kisspeptin-54? Kisspeptin-54 is the full-length precursor encoded by the KISS1 gene; kisspeptin-10 is the bioactive C-terminal decapeptide fragment that retains full GPR54 receptor potency and is the predominant form used in research.
• Can this be used in cell culture experiments? Yes, when properly reconstituted and diluted under sterile conditions for in vitro applications including GPR54-expressing cell lines.